NKX2.5 Antibody (3C1) Summary
| Immunogen |
NKX2-5 (NP_004378, 1 a.a. – 130 a.a.) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MFPSPALTPTPFSVKDILNLEQQQRSLAAAGELSARLEATLAPSSCMLAAFKPEAYAGPEAAAPGLPELRAELGRAPSPAKCASAFPAAPAFYPRAYSDPDPAKDPRAEKKELCALQKAVELEKTEADNA*
|
| Marker |
Cardiac Progenitor Marker
|
| Specificity |
NKX2-5 (3C1)
|
| Isotype |
IgG2a Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
NKX2-5
|
| Purity |
IgG purified
|
| Innovators Reward |
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Antibody reactivity against recombinant protein on ELISA.
|
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
IgG purified
|
Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for NKX2.5 Antibody (3C1)
- cardiac-specific homeo box
- cardiac-specific homeobox 1
- Cardiac-specific homeobox
- CHNG5
- CSX1
- CSXFLJ97195
- FLJ52202
- FLJ99536
- Homeobox protein CSX
- Homeobox protein NK-2 homolog E
- homeobox protein Nkx-2.5
- NK2 transcription factor related, locus 5 (Drosophila)
- NKX2.5
- NKX2.5FLJ97166
- NKX2-5
- NKX2E
- NKX2EFLJ97197
- NKX4-1
- tinman paralog
Background
Homeobox-containing genes play critical roles in regulating tissue-specific gene expression essential for tissue differentiation, as well as determining the temporal and spatial patterns of development (Shiojima et al., 1995 [PubMed 7665173]). It has been demonstrated that a Drosophila homeobox-containing gene called tinman is expressed in the developing dorsal vessel and in the equivalent of the vertebrate heart. Mutations in tinman result in loss of heart formation in the embryo, suggesting that tinman is essential for Drosophila heart formation. Furthermore, abundant expression of Csx, the presumptive mouse homolog of tinman, is observed only in the heart from the time of cardiac differentiation. CSX, the human homolog of murine Csx, has a homeodomain sequence identical to that of Csx and is expressed only in the heart, again suggesting that CSX plays an important role in human heart formation.[supplied by OMIM]