GMPS Antibody (1D10)

Product: NPS-2144 (hydrochloride)

GMPS Antibody (1D10) Summary

Immunogen
GMPS (NP_003866, 108 a.a. – 215 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. QMMNKVFGGTVHKKSVREDGVFNISVDNTCSLFRGLQKEEVVLLTHGDSVDKVADGFKVVARSGNIVAGIANESKKLYGAQFHPEVGLTENGKVILKNFLYDIAGCSG
Specificity
GMPS – guanine monphosphate synthetase
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
GMPS
Purity
IgG purified
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Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
  • Immunohistochemistry-Paraffin
Application Notes
Antibody reactivity against recombinant protein for WB. It has been used for IHC-P and ELISA.
Publications
Read Publication using H00008833-M01.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

Quality control test: Antibody Reactive Against Recombinant Protein.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for GMPS Antibody (1D10)

  • EC 6.3.5.2
  • Glutamine amidotransferase
  • GMP synthase [glutamine-hydrolyzing]
  • GMP synthase
  • GMP synthetase
  • guanine monphosphate synthetase
  • guanosine 5-monophosphate synthase
  • MLL/GMPS fusion protein

Background

In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP.

PMID: 23292653