RASGRP2 Antibody (3D8) Summary
| Immunogen |
RASGRP2 (NP_005816, 65 a.a. ~ 165 a.a) partial recombinant protein with GST tag.GTLDLDKGCTVEELLRGCIEAFDDSGKVRDPQLVRMFLMMHPWYIPSSQLAAKLLHIYQQSRKDNSNSLQVKTCHLVRYWISAFPAEFDLNPELAEQIKE
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| Specificity |
RASGRP2 (3D8)
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| Isotype |
IgG2a Kappa
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| Clonality |
Monoclonal
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| Host |
Mouse
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| Gene |
RASGRP2
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| Purity |
IgG purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
Antibody reactive against recombinant protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.
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| Publications |
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Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
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| Buffer |
PBS (pH 7.4)
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| Preservative |
No Preservative
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| Purity |
IgG purified
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Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for RASGRP2 Antibody (3D8)
- Calcium and DAG-regulated guanine nucleotide exchange factor I
- CALDAG-GEFI
- CDC25Lcalcium and diacylglycerol-regulated guanine nucleotide exchange factor I
- Cdc25-like protein
- F25B3.3 kinase-like protein
- guanine exchange factor MCG7
- hCDC25L
- MCG7
- RAS guanyl nucleotide-releasing protein 2
- RAS guanyl releasing protein 2 (calcium and DAG-regulated)
- RAS guanyl-releasing protein 2
Background
The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Three alternatively spliced transcript variants encoding the same protein have been found for this gene.