tropomyosin-3 Antibody (2E4.) Summary
| Immunogen |
TPM3 (AAH15403, 1 a.a. – 248 a.a.) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKRLSAAEEKYSQKEDKYEGEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQTLLDLNEM
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| Specificity |
TPM3 – tropomyosin 3 (2E4)
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| Isotype |
IgG2a Kappa
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| Clonality |
Monoclonal
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| Host |
Mouse
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| Gene |
TPM3
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| Purity |
IgG purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.
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| Publications |
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Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
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| Buffer |
PBS (pH 7.4)
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| Preservative |
No Preservative
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| Purity |
IgG purified
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Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for tropomyosin-3 Antibody (2E4.)
- cytoskeletal tropomyosin TM30
- FLJ41118
- gamma-tropomyosin
- heat-stable cytoskeletal protein 30 kDa
- hscp30
- hTM5
- MGC14582
- MGC3261
- MGC72094
- NEM1
- OK/SW-cl.5
- TM3
- TM30
- TM30nm
- TM-5
- TPMsk3
- TRK
- tropomyosin 3
- tropomyosin alpha-3 chain
- tropomyosin gamma
- tropomyosin-3
- tropomyosin-5
Background
This gene encodes a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Mutations in this gene result in autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are associated with cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]