HMGA2 Antibody (1D8) Summary
| Immunogen |
HMGA2 (NP_003474, 1 a.a. – 92 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MSARGEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSPSKAAQKKAEATGEKRPRGRPRKWPQQVVQKKP
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| Specificity |
HMGA2 – high mobility group AT-hook 2 (1D8)
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| Isotype |
IgG1 Kappa
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| Clonality |
Monoclonal
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| Host |
Mouse
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| Gene |
HMGA2
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| Purity |
IgG purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.
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| Publications |
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Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
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| Buffer |
PBS (pH 7.4)
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| Preservative |
No Preservative
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| Purity |
IgG purified
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Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for HMGA2 Antibody (1D8)
- BABL
- BABLHMGI-C
- high mobility group AT-hook 2
- High mobility group AT-hook protein 2
- high mobility group protein HMGI-C
- high-mobility group (nonhistone chromosomal) protein isoform I-C
- High-mobility group protein HMGI-C
- HMGA2
- HMGIC
- HMGICSTQTL9
- LIPO
Background
This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]