Complement C4b Antibody (1F2) Summary
| Immunogen |
C4B (NP_000583 1347 a.a. – 1446 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. NNRQIRGLEEELQFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEANEDYEDYEYDELPAKDDPDAPLQPVTPLQLFEG
|
| Specificity |
C4B – complement component 4B (Childo blood group) (1F2)
|
| Isotype |
IgG2b Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
C4B
|
| Purity |
IgG purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.
|
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
IgG purified
|
Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for Complement C4b Antibody (1F2)
- basic C4
- Basic complement C4
- C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3
- C4B1
- C4B12
- C4B2
- C4B3
- C4FMGC164979
- CH
- Chido form of C4
- CO4C4B5
- complement C4-B
- complement C4B1a
- complement component 4B (Chido blood group)
- complement component 4B
- CPAMD3FLJ60561
- EC 2.1.1.144
- EC 2.7.11
Background
This gene encodes the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. In addition, this gene exists as a long form and a short form due to the presence or absence of a 6.4 kb endogenous HERV-K retrovirus in intron 9. [provided by RefSeq]