BubR1 Antibody (2G9) Summary
| Immunogen |
BUB1B (AAH18739, 1 a.a. – 130 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MAAVKKEGGALSEAMSLEGDEWELSKENVQPLRQGRIMSTLQGALAQESACNNTLQQQKRAFEYEIRFYTGNDPLDVWDRYISWTEQNYPQGGKESNMSTLLERAVEALQGEKRYYSDPRFLNLWLKLGR
|
| Specificity |
BUB1B – BUB1 budding uninhibited by benzimidazoles 1 homolog beta (yeast)
|
| Isotype |
IgG1 Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
BUB1B
|
| Purity |
IgG purified
|
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|
Applications/Dilutions
| Dilutions |
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| Application Notes |
Antibody reactivity against recombinant protein for WB. It has also been used for IF, IHC-P and ELISA.
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Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
IgG purified
|
Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for BubR1 Antibody (2G9)
- Bub1A
- BUBR1budding uninhibited by benzimidazoles 1 (yeast homolog), beta
- budding uninhibited by benzimidazoles 1 homolog beta (yeast)
- EC 2.7.11.1
- hBUBR1
- MAD3/BUB1-related protein kinase
- MAD3LBUB1beta
- Mitotic checkpoint kinase MAD3L
- Protein SSK1
- SSK1mitotic checkpoint serine/threonine-protein kinase BUB1 beta
Background
This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.