MRP3 Antibody (M3II-21) Summary
| Immunogen |
The antibody reacts with the MRP3 antigen.
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| Specificity |
M3II-21 reacts with an internal epitope of MRP3, a 190-200 kD transmembrane protein that is closely related to the multidrug resistance protein MRP1. M3II-21 was raised against a bacterial fusion protein of MRP3, containing amino acids 830-949 of the protein. M3II-21 does not cross-react with the human MDR1, MRP1, MRP2 or MRP5 gene products
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| Isotype |
IgG2b
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| Clonality |
Monoclonal
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| Host |
Mouse
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| Gene |
ABCC3
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| Purity |
Tissue culture supernatant
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Applications/Dilutions
| Dilutions |
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| Application Notes |
M3II-21 has potential value for detection of MRP3-mediated drug-resistance in human tumor samples. Immunocytochemistry: use 1:20-1:50 dil. on acetone or formaldehyde fixed cytospin preparations. For immunohistochemistry: use 1:20 on acetone fixed frozen sections. Western Blot: use 1:20-1:50 dil, and anti-Mouse HRP. Flow Cytometry: optimal conditions still to be defined.
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Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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| Buffer |
1 ml serum-free tissue culture supernatant with 0.25 mg/ml immunoglobulin and 0.7% BSA
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| Preservative |
0.1% Sodium Azide
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| Purity |
Tissue culture supernatant
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Alternate Names for MRP3 Antibody (M3II-21)
- ABC31
- ATP-binding cassette sub-family C member 3
- ATP-binding cassette, sub-family C (CFTR/MRP), member 3
- canalicular multispecific organic anion transporter 2
- canicular multispecific organic anion transporter
- cMOAT2
- EC 3.6.3
- EC 3.6.3.44
- EC 6.3.2.4
- MLP2DKFZp686E22157
- MRP3MOAT-DEST90757
- multidrug resistance associated protein
- Multidrug resistance-associated protein 3
- Multi-specific organic anion transporter D