Integrin alpha 2/CD49b Antibody (235033) [Phycoerythrin]

Product: Torin 3

Integrin alpha 2/CD49b Antibody (235033) [Phycoerythrin] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse Integrin alpha 2/CD49b
Tyr27-Thr1129
Accession # Q62469
Specificity
Detects mouse Integrin alpha 2/CD49b in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant mouse Integrin alpha 3, alpha 4, alpha 5, alpha E, or alpha V is observed.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Rat
Gene
ITGA2
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Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Integrin alpha 2/CD49b Antibody (235033) [Phycoerythrin]

  • alpha-2 subunit
  • CD49b antigen
  • CD49b
  • Integrin alpha 2
  • integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
  • ITGA2
  • VLA 2
  • VLA-2 alpha

Background

The Integrin alpha 2 subunit, also known as CD49b and VLA-2 alpha subunit, forms a heterodimer with beta 1 Integrin. The alpha 2 beta 1 Integrin is a collagen receptor that binds expressing cells to collagen and regulates collagen and collagenase secretion. Notably, this subunit has an “I” domain that is resistant to proteolysis. Over amino acids
(aa) 27-1129, mouse Integrin alpha 2 shares 80% aa sequence identity with human Integrin alpha 2.

PMID: 9543090