Product: Folinic acid (Calcium)
Serpin A1/alpha 1-Antitrypsin Antibody (AAT/1378) Summary
| Immunogen |
Recombinant human Alpha-1-Antitrypsin (AAT) protein fragment
|
| Localization |
Cytoplasmic
|
| Marker |
Hepatocellular & Histiocytic Marker
|
| Specificity |
It recognizes a protein of 54kDa, which is identified antitrypsin (AAT). The immunohistochemical staining of AAT is useful in identification of benign and malignant hepatic tumors and yolk sac carcinomas. Positive staining for AAT is also used in detection of benign and malignant lesions of histiocytic nature. This antibody is may also useful tool in the screening of patients with cryptogenic cirrhosis or other forms of liver disease with fibrosis of uncertain origin.
|
| Isotype |
IgG
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
SERPINA1
|
| Purity |
Protein A or G purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Human Chromosome Location: 14q32.1
Immunohistology (Formalin-fixed) (0.5-1ug/ml for 30 minutes at RT) (Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes) |
| Theoretical MW |
54 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Packaging, Storage & Formulations
| Storage |
Store at 4C.
|
| Buffer |
10mM PBS and 0.05% BSA
|
| Preservative |
0.05% Sodium Azide
|
| Purity |
Protein A or G purified
|
Alternate Names for Serpin A1/alpha 1-Antitrypsin Antibody (AAT/1378)
- A1A
- A1AT
- AATMGC23330
- alpha 1-Antitrypsin
- alpha 1-Proteinase Inhibitor
- Alpha-1 protease inhibitor
- Alpha-1-antiproteinase
- alpha-1-antitrypsin
- antitrypsin), member 1
- member 1
- PIMGC9222
- serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase
- serine (or cysteine) proteinase inhibitor, clade A, member 1
- Serpin A1
- serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin)