Prolactin R Antibody (B6.2 PRLR742) – IHC-Prediluted Summary
| Immunogen |
Semi-purified human prolactin receptor (B6.2); Recombinant human prolactin receptor (PRLR742)
|
| Localization |
Cell surface and cytoplasmic
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| Specificity |
It recognizes a protein of 70kDa, identified as prolactin receptor. Prolactin is a pituitary hormone involved in the stimulation of milk production, salt and water regulation, growth, development and reproduction. The initial step in its action is the binding to a specific membrane receptor (prolactin receptor), which belongs to the superfamily of class 1 cytokine receptors. The function of the prolactin receptor is mediated, at least in part, by two families of signaling molecules: Janus kinases and signal transducers and activators of transcription.
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| Isotype |
IgG
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| Clonality |
Monoclonal
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| Host |
Mouse
|
| Gene |
PRLR
|
| Purity |
Protein A or G purified
|
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Applications/Dilutions
| Dilutions |
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| Application Notes |
Hu-chromosome location: 5p13.2
Immunohistochemistry-Paraffin 0.5 – 1 ug/ml for 30 minutes at RT; Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10 – 20 min followed by cooling at RT for 20 minutes. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
| Theoretical MW |
70 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Packaging, Storage & Formulations
| Storage |
Store at 4C.
|
| Buffer |
10mM PBS and 0.05% BSA
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| Preservative |
0.05% Sodium Azide
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| Purity |
Protein A or G purified
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Alternate Names for Prolactin R Antibody (B6.2 PRLR742) – IHC-Prediluted
- delta 4-delta 7/11 truncated prolactin receptor
- delta 4-SF1b truncated prolactin receptor
- hPRL receptor
- hPRLrI
- PRLR
- PRL-R
- Prolactin R
- prolactin receptor delta 7/11
- prolactin receptor
- ProlactinR
- secreted prolactin binding protein