Napsin-A Antibody (NAPSA/1238) Summary
| Immunogen |
Recombinant fragment of human Napsin-A protein
|
| Localization |
Cytoplasmic
|
| Marker |
Lung Adenocarcinoma Marker
|
| Specificity |
Napsin is a pepsin-like aspartic proteinase connected with maturation of surfactant protein B.There are two closely related napsins, napsin A and napsin B. Napsin A is expressed as a single chain protein. Immunohistochemical studies revealed high expression levels of napsin A in human lung and kidney but low expression in spleen. Napsin A is expressed in type II pneumocytes and in adenocarcinomas of lung. The high specificity expression of napsin A in adenocarcinomas of lung is useful to distinguish primary lung adenocarcinomas from adenocarcinomas of other organs.
|
| Isotype |
IgG Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
NAPSA
|
| Purity |
Protein A purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Hu-chromosome location: 19q13.33
Immunohistochemistry-Paraffin 1 – 2 ug/ml for 30 minutes at RT; Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate buffer, pH 6.0, for 10 – 20 min followed by cooling at RT for 20 minutes. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
| Theoretical MW |
37 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Packaging, Storage & Formulations
| Storage |
Store at 4C.
|
| Buffer |
10mM PBS and 0.05% BSA
|
| Preservative |
0.05% Sodium Azide
|
| Purity |
Protein A purified
|
Alternate Names for Napsin-A Antibody (NAPSA/1238)
- Asp 4
- ASP4
- Aspartyl protease 4
- EC 3.4.23
- EC 3.4.23.-
- EC 3.4.23.15
- EC 3.4.23.3
- EC 3.4.23.5
- KAP
- Kdap
- NAP1napsin-A
- NAPA
- NAPApronapsin A
- NAPSA
- napsin A aspartic peptidase
- Napsin A
- Napsin-1
- SNAPA
- TA01/TA02