Cytokeratin 7 Antibody (KRT7/760) [DyLight 405] Summary
| Immunogen |
Recombinant full-length human KRT7 protein
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| Localization |
Cytoplasmic
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| Marker |
Glandular and Transitional Epithelial Marker
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| Specificity |
It recognizes an intermediate filament protein (IFP) of 55kDa, which is identified as cytokeratin 7. This MAb is highly specific to cytokeratin 7 and shows no cross-reaction with other IFPs. Cytokeratin 7 is a basic cytokeratin, which is found in most glandular and transitional epithelia but not in the stratified squamous epithelia. Keratin 7 is expressed in the epithelial cells of ovary, lung, and breast but not of colon, prostate, or gastrointestinal tract. This MAb is highly useful in distinguishing ovarian carcinomas (keratin 7+) from colon carcinomas (keratin 7-).
|
| Isotype |
IgG1
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| Clonality |
Monoclonal
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| Host |
Mouse
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| Gene |
KRT7
|
| Purity |
Protein A or G purified
|
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Applications/Dilutions
| Dilutions |
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| Application Notes |
Optimal dilution of this antibody shomld be experimentally determined.
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Packaging, Storage & Formulations
| Storage |
Store at 4C in the dark.
|
| Buffer |
50mM Sodium Borate
|
| Preservative |
0.05% Sodium Azide
|
| Purity |
Protein A or G purified
|
Notes
Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
Alternate Names for Cytokeratin 7 Antibody (KRT7/760) [DyLight 405]
- CK7
- CK-7
- cytokeratin 7
- cytokeratin-7
- K2C7
- K7keratin, 55K type II cytoskeletal
- keratin 7
- keratin, type II cytoskeletal 7
- keratin-7
- MGC129731
- MGC3625
- sarcolectin
- SCLkeratin, simple epithelial type I, K7
- type II mesothelial keratin K7
- Type-II keratin Kb7