CXCR5 Antibody Summary
| Immunogen |
Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human CXCR5.
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| Localization |
Multi-pass membrane protein
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| Specificity |
Human CXCR5. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except MTA3 (50%).
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| Predicted Species |
Mouse (94%), Rat (94%), Porcine (94%), Hamster (94%), Bovine (94%), Rabbit (94%), Canine (94%). Backed by our 100% Guarantee.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
CXCR5
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Publications |
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Reactivity Notes
Gorilla, Gibbon. Predicted cross-reactivity based on sequence identity: Panda (94%).
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
PBS
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| Preservative |
0.1% Sodium Azide
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| Concentration |
1.0 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for CXCR5 Antibody
- BLR1
- BLR1MDR-15
- Burkitt lymphoma receptor 1
- Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif)receptor 5)
- Burkitt lymphoma receptor 1, GTP-binding protein
- CD185 antigen
- CD185
- chemokine (C-X-C motif) receptor 5
- C-X-C chemokine receptor type 5
- CXCR5
- CXC-R5
- MDR15CXCR-5
- MGC117347
- Monocyte-derived receptor 15
Background
CXCR5, a Chemokine Receptor, also called Burkitts lymphoma receptor 1, is required for normal development of Peyers patches, inguinal lymph nodes, and splenic follicles. CXCR5 binds B-lymphocyte chemoattractant (BLC) and is involved in B-cell homing to follicles in lymph nodes and spleen. Two isoforms are produced by alternative splicing. CXCR5 expression has been reported in human blood and salivary gland and in animal lymphatic organs, blood, bone marrow, brain, liver, lymph node, skin, spleen, stomach, and tonsil. ESTs have been isolated from human brain, germ cell, lung, lymph, pancreas, skin, stomach, and uterus cancer libraries, and from normal human blood, liver/spleen, lymph node, nerve, placenta, small intestine, tonsil, and B-cell/lung/testis libraries.