PSD-95 Antibody (7E3-1B8) Summary
| Immunogen |
Recombinant rat PSD-95.
|
| Marker |
post-Synaptic Marker
|
| Isotype |
IgG2a
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
DLG4
|
| Purity |
Protein G purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
This antibody is useful in Western Blot (Detects a band of ~95kDa).
|
Reactivity Notes
Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.
Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.2) and 50% Glycerol
|
| Preservative |
0.09% Sodium Azide
|
| Purity |
Protein G purified
|
Alternate Names for PSD-95 Antibody (7E3-1B8)
- discs, large homolog 4 (Drosophila)
- disks large homolog 4
- DLG4
- FLJ97752
- FLJ98574
- Postsynaptic density protein 95
- post-synaptic density protein 95
- PSD95
- PSD-95
- PSD95SAP90SAP-90discs large homolog 4
- SAP90
- Synapse-associated protein 90
- Tax interaction protein 15
Background
Postsynaptic density protein 95 kDa (PSD-95), also known as Synapse associated protein 90 kDa (SAP90), is a brain specific protein that is highly similar to the Drosophila dlg tumor suppressor protein. PSD-95 is a member of membrane associated proteins that are localized beneath the postsynaptic membrane of synapses in the CNS. PSD-95 interacts with NMDA receptor and Shaker-type K+ channels and contributes to their clustering and localization at the synaptic spines in hippocampal neurons and the pinceau terminal of cerebellar basket cells, respectively.