MMP-17 Antibody Summary
| Immunogen |
This antibody is specific for the C Terminus Region of the target protein.
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| Specificity |
This product is specific for Human MMP17.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
MMP17
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
This antibody is useful in ELISA and Western Blot.
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| Publications |
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Reactivity Notes
Human.
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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| Buffer |
20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
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| Preservative |
No Preservative
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| Purity |
Immunogen affinity purified
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Notes
Manufactured by SDIXs proprietary Genomic Antibody Technology™. GAT FAQs.
Alternate Names for MMP-17 Antibody
- matrix metallopeptidase 17 (membrane-inserted)
- matrix metalloproteinase 17 (membrane-inserted)
- matrix metalloproteinase-17
- membrane-type matrix metalloproteinase 4
- membrane-type-4 matrix metalloproteinase
- MMP17
- MMP-17
- MT4MMP
- MT4-MMP
- MT-MMP 4
- MTMMP4
Background
Membrane type (MT) matrix metalloproteinases (MMPs) are recently recognized members of the family of Zn(2+)- and Ca(2+)-dependent MMPs. MMP-17 is, therefore, a competent Zn(2+)-dependent MMP with unique specificity among synthetic substrates and the capability to both degrade gelatin and activate progelatinase A (1). (MMP-17) is expressed mainly in the brain, leukocytes, the colon, the ovary, and the testis. The expression of MMP-17 in leukocytes together with its putative membrane localization suggest that this enzyme could be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators such as tumor necrosis factor-alpha (2). glycosylphospha-tidylinositol (GPI) anchoring of MT4-MMP on the cell surface indicates a unique biological function and character for this proteinase (3).