p21/CIP1/CDKN1A Antibody Summary
| Immunogen |
This antibody is specific for the entire range of the target protein.
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| Specificity |
This product is specific for Human CDKN1A.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
CDKN1A
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
This antibody is useful in ELISA, Western Blot and Immunohistochemistry-Paraffin.
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| Publications |
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Reactivity Notes
Human.
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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| Buffer |
20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
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| Preservative |
No Preservative
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| Purity |
Immunogen affinity purified
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Notes
Manufactured by SDIXs proprietary Genomic Antibody Technology™. GAT FAQs.
Alternate Names for p21/CIP1/CDKN1A Antibody
- CAP20cyclin-dependent kinase inhibitor 1
- CDK-interacting protein 1
- CDKN1A
- CDKN1melanoma differentiation associated protein 6
- CIP1
- CIP1WAF1CDK-interaction protein 1
- cyclin-dependent kinase inhibitor 1A (p21, Cip1)
- MDA6
- MDA-6
- Melanoma differentiation-associated protein 6
- p21
- p21CIP1
- p21Cip1/Waf1
- PIC1
- SDI1DNA synthesis inhibitor
- wild-type p53-activated fragment 1
Background
Cell cycle progression is regulated by cyclins and their cognate Cdks. p21 (WAF1/CIP1) inhibits the activity of each member of the cyclin/Cdk family, and overexpression of this protein inhibits the proliferation of mammalian cells. The expression of p21 is inducible by a wide range of stress stimuli. p21 is tightly regulated at the transcriptional level by p53, and probably serves as the effector of p53 cell cycle control.