Product: 2,5-Pyrimidinediamine with linker
KDEL Antibody Summary
| Immunogen |
This antibody is specific for the N Terminus Region of the target protein.
|
| Marker |
Endoplasmic Reticulum Marker
|
| Specificity |
This product is specific for Human KDELC1.
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
KDELC1
|
| Purity |
Immunogen affinity purified
|
| Innovators Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovators Reward
|
Applications/Dilutions
| Dilutions |
|
|
| Application Notes |
This antibody is useful in ELISA, Immunohistochemistry-Paraffin and Western Blot.
|
|
| Publications |
|
Reactivity Notes
Human.
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
|
| Preservative |
No Preservative
|
| Purity |
Immunogen affinity purified
|
Notes
Manufactured by SDIXs proprietary Genomic Antibody Technology™. GAT FAQs.
Alternate Names for KDEL Antibody
- Endoplasmic reticulum resident protein 58
- EP58KDEL1
- ER protein 58
- ERp58
- KDEL (Lys-Asp-Glu-Leu) containing 1
- KDEL motif-containing 1
- KDEL motif-containing protein 1
- MGC5302
Background
The sequence Lys-Asp-Glu-Leu (KDEL) or a closely related sequence, is present at the carboxy-terminus of soluble endoplasmic reticulum (ER) resident proteins and some membrane proteins. 78 and 94 kDa glucose regulated proteins (GRP 78) and GRP 94 respectively and protein disulfide isomerase (PDI) all share the C-terminal KDEL sequence. The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER. This retention is reported to be mediated by a KDEL receptor.