CA125/MUC16 Antibody Summary
| Immunogen |
This antibody is specific for the N Terminus Region of the target protein.
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| Specificity |
This product is specific for Human CA125
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
MUC16
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| Purity |
Immunogen affinity purified
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| Innovators Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions
| Dilutions |
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| Application Notes |
This antibody is useful in ELISA.
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| Publications |
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Reactivity Notes
Human.
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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| Buffer |
20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
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| Preservative |
No Preservative
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| Purity |
Immunogen affinity purified
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Notes
Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at [email protected] for more details.
Alternate Names for CA125/MUC16 Antibody
- CA125 ovarian cancer antigen
- CA125
- CA-125
- CA125MUC-16
- FLJ14303
- MUC16
- mucin 16, cell surface associated
- mucin-16
- Ovarian cancer-related tumor marker CA125
- Ovarian carcinoma antigen CA125
Background
MUC16 (CA125) is a serum marker that is used routinely in gynecologic practice to monitor patients with ovarian cancer. It is a mullerian duct differentiation antigen that is over expressed in epithelial ovarian cancer cells and secreted into the blood, although its expression is not entirely confined to ovarian cancer. Most biochemical studies have concluded that MUC16 is a high molecular mass glycoprotein, although estimates of its size range from 200 to 2000 kDa with smaller subunits being described by some investigators.