Aminopeptidase A/ENPEP Antibody (6C3) Summary
| Immunogen |
The immunogen for this antibody was Aminopeptidase A/APA.
|
| Isotype |
IgG2a Kappa
|
| Clonality |
Monoclonal
|
| Host |
Rat
|
| Gene |
ENPEP
|
| Purity |
Protein A or G purified
|
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|
Applications/Dilutions
| Dilutions |
|
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
|
| Buffer |
Aqueous, may contain carrier protein/stabilizer.
|
| Preservative |
0.09% Sodium Azide
|
| Concentration |
0.5 mg/ml
|
| Purity |
Protein A or G purified
|
Alternate Names for Aminopeptidase A/ENPEP Antibody (6C3)
- Aminopeptidase A
- APA
- AP-A
- CD249 antigen
- CD249
- Differentiation antigen gp160
- EAP
- EC 3.4.11
- EC 3.4.11.7
- ENPEP
- glutamyl aminopeptidase (aminopeptidase A)
- glutamyl aminopeptidase
- gp160
Background
The 6C3 monoclonal antibody reacts with mouse Ly-51 and 6C3 antigen. LY-51 is a 140 kDa type II transmembrane protein that is present on the surface as a disulfide-linked homodimer. This molecule is an enzyme with aminopeptidase A (APA) activity and is expressed by bone marrow stromal cells, thymic cortical epithelial cells and at early stages of mouse B cell development, on pre-B cells. The low level of LY-51 expression on pre-B cells can be upregulated in the presence of IL-7.