Product Name :
Rabbit anti-ATP5D Polyclonal Antibody(C-term)
Synonym :
ATP synthase subunit delta; mitochondrial; F-ATPase delta subunit; ATP5D
Host :
Rabbit
Species Reactivity:
Human, Mouse, Rat
Specificity :
This ATP5D antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 156-188 amino acids from the C-terminal region of human ATP5D.
Predicted Reactivity:
Bovine
Applications :
WB~~1:1000-1:4000
Immunogen:
Concentration :
Purification :
Clonality:
Polyclonal Antibody
Storage Temp.:
Maintain refrigerated at 2-8 ° C for up to 2 weeksFor long term storage store at -20 ° C in small aliquots to prevent free that cycles
Research areas :
Metabolism;Signal Transduction
Background :
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) – containing the extramembraneous catalytic core, and F(0) – containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP turnover in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.
UniProt :
P30049
Additional information:
Product Details FAQ Citations(0) Video Pictures Documents |Overview |Description Purified Rabbit Polyclonal Antibody (Pab) |Synonym ATP synthase subunit delta; mitochondrial; F-ATPase delta subunit; ATP5D |Host Rabbit |Specificity This ATP5D antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 156-188 amino acids from the C-terminal region of human ATP5D. |Species Reactivity Human, Mouse, Rat |Predicted Reactivity Bovine |Applications WB~~1:1000-1:4000 |Properties |Clonality Polyclonal Antibody |Isotype Rabbit Ig |Storage Temp. Maintain refrigerated at 2-8 ° C for up to 2 weeksFor long term storage store at -20 ° C in small aliquots to prevent free that cycles |Research areas Metabolism;Signal Transduction |Target |Background Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) – containing the extramembraneous catalytic core, and F(0) – containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP turnover in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits. |Cellular localization Mitochondrion. Mitochondrion inner membrane. |UniProt P30049 |References |References Jordan E.M.,et al.Biochim. Biophys. Acta 1130:123-126(1992).Halleck A.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.Grimwood J.,et al.Nature 428:529-535(2004).Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.Hochstrasser D.F.,et al.Electrophoresis 13:992-1001(1992). |Tips:This product is for research use only. Not for use in diagnostic prodcedures.
Rabbit anti-ATP5D Polyclonal Antibody(C-term)
Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.Related websites: https://www.medchemexpress.com/antibodies.html
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