Product Name :
FAPy-adenine
Description:
FAPy-adenine is an oxidized DNA base. Fapy-adenine shows an increased trend levels in the Alzheimer’s disease brain. Oxidized nucleosides are biochemical markers for tumors, aging, and neurodegenerative diseases.
CAS:
5122-36-1
Molecular Weight:
153.14
Formula:
C5H7N5O
Chemical Name:
N-(4,6-diaminopyrimidin-5-yl)formamide
Smiles :
NC1=NC=NC(N)=C1NC=O
InChiKey:
MVYUVUOSXNYQLL-UHFFFAOYSA-N
InChi :
InChI=1S/C5H7N5O/c6-4-3(10-2-11)5(7)9-1-8-4/h1-2H,(H,10,11)(H4,6,7,8,9)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
FAPy-adenine is an oxidized DNA base. Fapy-adenine shows an increased trend levels in the Alzheimer’s disease brain. Oxidized nucleosides are biochemical markers for tumors, aging, and neurodegenerative diseases.|Product information|CAS Number: 5122-36-1|Molecular Weight: 153.14|Formula: C5H7N5O|Chemical Name: N-(4,6-diaminopyrimidin-5-yl)formamide|Smiles: NC1=NC=NC(N)=C1NC=O|InChiKey: MVYUVUOSXNYQLL-UHFFFAOYSA-N|InChi: InChI=1S/C5H7N5O/c6-4-3(10-2-11)5(7)9-1-8-4/h1-2H,(H,10,11)(H4,6,7,8,9)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 17.86 mg/mL (116.63 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Vasopressin} MedChemExpress|{Vasopressin} Metabolic Enzyme/Protease|{Vasopressin} Purity & Documentation|{Vasopressin} References|{Vasopressin} supplier|{Vasopressin} Cancer} |Shelf Life: ≥12 months if stored properly.{{Chrysin} medchemexpress|{Chrysin} Estrogen Receptor/ERR|{Chrysin} Protocol|{Chrysin} Description|{Chrysin} supplier|{Chrysin} Cancer} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23756629 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|In the absence of the external field the FAPy-adenine is able to form pairs with all four canonical nucleic acid bases. In contrast, in the presence of the external field the mispairing abilities of FAPy-adenine become insignificant since the most stable dimers are formed with thymine.|In Vivo:|The nuclear DNA damage by oxygen-derived radicals is increased in Alzheimer’s disease and support the concept that the brain is under increased oxidative stress in Alzheimer’s disease.|Products are for research use only. Not for human use.|