n-Myc Antibody (3H4) Summary
| Immunogen |
MYCN (NP_005369, 1 a.a. – 100 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MPSCSTSTMPGMICKNPDLEFDSLQPCFYPDEDDFYFGGPDSTPPGEDIWKKFELLPTPPLSPSRGFAEHSSEPPSWVTEMLLENELWGSPAEEDAFGLG
|
| Localization |
Nuclear
|
| Specificity |
MYCN – v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
|
| Isotype |
IgG2a Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
MYCN
|
| Purity |
IgG purified
|
| Innovators Reward |
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Antibody reactivity against cell lysate and recombinant protein for WB. It has been used for RNAi Validation and ELISA.
|
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
IgG purified
|
Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for n-Myc Antibody (3H4)
- BHLHE37
- bHLHe37N-myc proto-oncogene protein
- Class E basic helix-loop-helix protein 37
- MODED
- neuroblastoma-derived v-myc avian myelocytomatosis viral related oncogene
- N-myc
- NMYCneuroblastoma MYC oncogene
- ODED
- oncogene NMYC
- pp65/67
- v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived
- v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
Background
This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas.