integrin beta 4 binding protein Antibody Summary
| Immunogen |
The immunogen for this product maps to a region between residue 50 and 100 of human Eukaryotic Translation Initiation Factor 6 using the numbering given in entry NP_852133.1 (GeneID 3692).
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
EIF6
|
| Purity |
Immunogen affinity purified
|
| Innovators Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovators Reward
|
Applications/Dilutions
| Dilutions |
|
Reactivity Notes
Human
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
|
| Buffer |
Tris-Citrate/Phosphate (pH 7.0 – 8.0)
|
| Preservative |
0.09% Sodium Azide
|
| Concentration |
1 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for integrin beta 4 binding protein Antibody
- B(2)GCN homolog
- b(2)gcn
- B4 integrin interactor
- CAB
- EIF3Ap27(BBP)
- eIF-6
- eukaryotic translation initiation factor 3A
- eukaryotic translation initiation factor 6
- ITGB4BPintegrin beta 4 binding protein
- p27 beta-4 integrin-binding protein
- p27BBP
Background
Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple transcript variants encoding two different isoforms have been found for this gene.