Product: Primaquine (Diphosphate)
gp130/CD130 Antibody Summary
| Immunogen |
This antibody is specific for the Middle Region of the target protein.
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| Specificity |
This product is specific for Human IL6ST.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
IL6ST
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
This antibody is useful in ELISA and Western Blot.
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| Publications |
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Reactivity Notes
Human.
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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| Buffer |
20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
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| Preservative |
No Preservative
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| Purity |
Immunogen affinity purified
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Notes
Manufactured by SDIXs proprietary Genomic Antibody Technology™. GAT FAQs.
Alternate Names for gp130/CD130 Antibody
- CD130 antigen
- CD130
- CDw130
- DKFZp564F053
- gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form
- gp130
- IL-6 receptor subunit beta
- IL-6R subunit beta
- IL-6RB
- IL-6R-beta
- IL6ST
- interleukin 6 signal transducer (gp130, oncostatin M receptor)
- interleukin receptor beta chain
- interleukin-6 receptor subunit beta
- Interleukin-6 signal transducer
- Membrane glycoprotein 130
- membrane glycoprotein gp130
- Oncostatin-M receptor subunit alpha
Background
The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq]