c-Myc Antibody (MYC275) [DyLight 350] Summary
| Immunogen |
Recombinant human c-myc protein
|
| Localization |
Nuclear
|
| Specificity |
The c-Myc protein is a transcription factor, which is encoded by the c-Myc gene on human chromosome 8q24. c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin dependent kinase, ERK2 and C-Jun N terminal Kinase (JNK) in cell proliferation and cell cycle regulation. Studies also have shown that c-Myc is essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells, and which brought extensive attention in the development of new therapeutic approach for cancer treatment.
|
| Isotype |
IgG1 Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
MYC
|
| Purity |
Protein A or G purified
|
| Innovators Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovators Reward
|
Applications/Dilutions
| Dilutions |
|
Packaging, Storage & Formulations
| Storage |
Store at 4C in the dark.
|
| Buffer |
50mM Sodium Borate
|
| Preservative |
0.05% Sodium Azide
|
| Purity |
Protein A or G purified
|
Alternate Names for c-Myc Antibody (MYC275) [DyLight 350]
- avian myelocytomatosis viral oncogene homolog
- BHLHE39
- bHLHe39MRTL
- Class E basic helix-loop-helix protein 39
- cMyc
- c-Myc
- myc proto-oncogene protein
- Myc
- Myc2
- MYCC
- myc-related translation/localization regulatory factor
- Niard
- Nird
- Proto-oncogene c-Myc
- Transcription factor p64
- v-myc avian myelocytomatosis viral oncogene homolog
- v-myc myelocytomatosis viral oncogene homolog (avian)