alpha-Fetoprotein/AFP Antibody (C2) [DyLight 650] Summary
| Immunogen |
Alpha fetoprotein (AFP) purified from serum of a hepatoma patient.
|
| Localization |
Cytoplasmic
|
| Marker |
Hepatocellular/Germ Cell Tumor Marker
|
| Specificity |
It recognizes an oncofetal glycoprotein with a single chain of 70kDa, which is identified as alpha fetoprotein (AFP) (ISOBM TD-2 workshop). This MAb is highly specific to AFP and shows no cross-reaction with other oncofetal antigens or serum albumin. AFP is normally synthesized in the liver, intestinal tract, and yolk sac of the fetus. Antibody to AFP has been shown to be useful in detecting hepatocellular carcinomas (HCC) and germ cell neoplasms, especially yolk sac tumors.
|
| Isotype |
IgG1 Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
AFP
|
| Purity |
Protein A or G purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Optimal dilution of this antibody should be experimentally determined.
|
Packaging, Storage & Formulations
| Storage |
Store at 4C in the dark.
|
| Buffer |
50mM Sodium Borate
|
| Preservative |
0.05% Sodium Azide
|
| Purity |
Protein A or G purified
|
Notes
Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
Alternate Names for alpha-Fetoprotein/AFP Antibody (C2) [DyLight 650]
- AFP
- Alpha-1-fetoprotein
- alpha-fetoglobulin
- alpha-Fetoprotein
- DSCAM2
- FETA
- HP
- HPAFP