alpha 2-Macroglobulin-like 1/A2ML1 Antibody Summary
| Immunogen |
A2ML1 (AAH93840.1, 1 a.a. ~ 158 a.a) full-length human protein.MYTLEASGQGCVYVQTVLRYNILPPTNMKTFSLSVEIGKARCEQPTSPRSLTLTIHTSYVGSRSSSNMAIVEVKMLSGFSPMEGTNQLLLQQPLVKKVEFGTDTLNIYLDELIKNTQTYTFTISQSVLVTNLKPATIKVYDYYLPDEQATIQYSDPCE
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| Specificity |
A2ML1 – alpha-2-macroglobulin-like 1,
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| Clonality |
Polyclonal
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| Host |
Mouse
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| Gene |
A2ML1
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| Purity |
Protein A purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control.
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| Publications |
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Reactivity Notes
Human.
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
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| Buffer |
PBS (pH 7.4)
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| Preservative |
No Preservative
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| Purity |
Protein A purified
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Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for alpha 2-Macroglobulin-like 1/A2ML1 Antibody
- A2ML1
- alpha 2Macroglobulin like 1
- alpha 2-Macroglobulin-like 1
- alpha-2-macroglobulin-like 1
- alpha-2-macroglobulin-like protein 1
- C3 and PZP-like, alpha-2-macroglobulin domain containing 9
- CPAMD9
Background
The alpha-macroglobulin (AM) superfamily of proteins contains both complement components and protease inhibitors, including A2M (MIM 103950) and A2ML1. AM proteins display a unique trap mechanism of inhibition, by which the AM inhibitor undergoes a major conformational change upon its cleavage by a protease, thus trapping the protease and blocking it from subsequent substrate binding (Galliano et al., 2006 [PubMed 16298998]).[supplied by OMIM]