Product: Dehydroisoandrosterone 3-acetate
YARS Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the C-terminus region of human Tyrosyl tRNA synthetase. The exact sequence is proprietary.
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| Localization |
Cytoplasm
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| Isotype |
IgG
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
YARS
|
| Purity |
Immunogen affinity purified
|
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Applications/Dilutions
| Dilutions |
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Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
0.25 mg/ml
|
| Purity |
Immunogen affinity purified
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Alternate Names for YARS Antibody
- CMTDIC
- EC 6.1.1
- EC 6.1.1.1
- Tyrosyl–tRNA ligase
- tyrosyl-tRNA synthetase
- tyrosyl-tRNA synthetase, cytoplasmic
- TYRRS
- YRStyrRS
- YTStyrosine tRNA ligase 1, cytoplasmic
Background
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine.