XPD Antibody Summary
| Immunogen |
This antibody is specific for the N Terminus Region of the target protein.
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| Specificity |
This product is specific for Human ERCC2.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
ERCC2
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
This antibody is useful in ELISA, Western Blot and Immunohistochemistry-Paraffin.
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| Publications |
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Reactivity Notes
Human.
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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| Buffer |
20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
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| Preservative |
No Preservative
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| Purity |
Immunogen affinity purified
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Notes
Manufactured by SDIXs proprietary Genomic Antibody Technology™. GAT FAQs.
Alternate Names for XPD Antibody
- Basic transcription factor 2 80 kDa subunit
- BTF2 p80
- COFS2
- CXPD
- DNA excision repair protein ERCC-2
- DNA repair protein complementing XP-D cells
- EC 3.6.1
- EC 3.6.4.12
- EM9
- EM9TFIIH basal transcription factor complex 80 kDa subunit
- ERCC2
- excision repair cross-complementing rodent repair deficiency, complementationgroup 2
- MAG
- MGC102762
- MGC126218
- MGC126219
- TFIIH 80 kDa subunit
- TFIIH basal transcription factor complex helicase subunit
- TFIIH basal transcription factor complex helicase XPD subunit
- TTD
- xeroderma pigmentosum complementary group D
- Xeroderma pigmentosum group D-complementing protein
- XPD
- XPDC
- XPDTFIIH p80
Background
The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]