Product: Rhosin (hydrochloride)
WISP2 Antibody Summary
| Immunogen |
This antibody is specific for the C Terminus Region of the target protein.
|
| Specificity |
This product is specific for Human WISP2.
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
WISP2
|
| Purity |
Immunogen affinity purified
|
| Innovators Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovators Reward
|
Applications/Dilutions
| Dilutions |
|
|
| Application Notes |
This antibody is useful in ELISA, Immunohistochemistry-Paraffin and Western Blot.
|
|
| Publications |
|
Reactivity Notes
Human.
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
|
| Preservative |
No Preservative
|
| Purity |
Immunogen affinity purified
|
Notes
Manufactured by SDIXs proprietary Genomic Antibody Technology™. GAT FAQs.
Alternate Names for WISP2 Antibody
- CCN5CCN family member 5
- Connective tissue growth factor-like protein
- Connective tissue growth factor-related protein 58
- CT58CTGF-Lwnt-1 signaling pathway protein 2
- CTGFL
- WISP-2
- WNT1 inducible signaling pathway protein 2
- WNT1-inducible-signaling pathway protein 2
Background
This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like (CT) domain. The encoded protein lacks the CT domain which is implicated in dimerization and heparin binding. It is 72% identical to the mouse protein at the amino acid level. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Its expression in colon tumors is reduced while the other two WISP members are overexpressed in colon tumors. It is expressed at high levels in bone tissue, and may play an important role in modulating bone turnover.