VGF Antibody Summary
| Immunogen |
The antiserum was produced against synthesized peptide derived from human VGF. The immunogen region is: C-terminal.
|
| Specificity |
VGF Antibody detects endogenous levels of total VGF protein.
|
| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
VGF
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| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
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Reactivity Notes
Human,Mouse, Rat
Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (without Mg2+ and Ca2+, pH 7.4), 0.15M NaCl and 50% Glycerol
|
| Preservative |
0.02% Sodium Azide
|
| Concentration |
1 mg/ml
|
| Purity |
Immunogen affinity purified
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Alternate Names for VGF Antibody
- neuro-endocrine specific protein VGF
- neurosecretory protein VGF
- VGF nerve growth factor inducible
- VGF
Background
Nerve growth factor (NGF) is a peptide that plays a key role in the differentiation and survival of neurons in the peripheral nervous system (PNS) and the central nervous system (CNS). VGF is a peptide synthesized and secreted by neurons and is upregulated by NGF in the PC12 cell line. VGF is widely expressed in both the PNS and CNS, but is especially abundant in the adult hypothalamus. VGF plays an essential role in how the brain regulates energy expenditure and body weight. Its expression is rapidly induced by injury, the circadian clock, and neuronal activity.