VE-Cadherin Antibody (16B1) Summary
| Immunogen |
The immunogen for this antibody is VE Cadherin.
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| Marker |
Endothelial Cell Marker
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| Isotype |
IgG1
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| Clonality |
Monoclonal
|
| Host |
Mouse
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| Gene |
CDH5
|
| Purity |
Protein A or G purified
|
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Applications/Dilutions
| Dilutions |
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| Application Notes |
This 16B1 antibody has been tested by immunoblotting Human Umbilical Vein Endothelial Cell (HUVEC) lysates. This 16B1 antibody has also been reported for use in flow cytometric analysis and immunocytochemistry.
|
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
|
| Buffer |
Aqueous, may contain carrier protein/stabilizer.
|
| Preservative |
0.09% Sodium Azide
|
| Purity |
Protein A or G purified
|
Alternate Names for VE-Cadherin Antibody (16B1)
- 7B4 antigen
- 7B4
- cadherin 5, type 2 (vascular endothelium)
- cadherin 5, type 2, VE-cadherin (vascular epithelium)
- Cadherin-5
- CD144 antigen
- CD144
- CDH5
- endothelial-specific cadherin
- FLJ17376
- Vascular endothelial cadherin
- VECadherin
- VE-Cadherin
Background
The 16B1 antibody reacts with human CD144, also known as VE-cadherin and cadherin-5. The cadherin family of receptors, which are calciumdependent adhesion molecules, is known to be involved in homophilic cell interactions. VE-cadherin, which is 140 kDa, is localized at theintercellular boundaries of endothelial cells in blood and lymphatic vessels in several tissues. It is thought to play a role in vascular permeability and remodeling.