UbcH5c/UBE2D3 Antibody (4C1-1E3) Summary
| Immunogen |
UBE2D3 (AAH03395, 1 a.a. – 147 a.a.) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRISREWTQKYAM
|
| Specificity |
UBE2D3 – ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)
|
| Isotype |
IgG1 Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
UBE2D3
|
| Purity |
IgG purified
|
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Applications/Dilutions
| Dilutions |
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| Application Notes |
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for ELISA.
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Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
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| Buffer |
PBS (pH 7.4)
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| Preservative |
No Preservative
|
| Purity |
IgG purified
|
Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for UbcH5c/UBE2D3 Antibody (4C1-1E3)
- E2(17)KB 3
- E2(17)KB3
- EC 6.3.2.19
- MGC43926
- MGC5416
- UBC4/5
- UBC5C
- UbcH5c
- UBE2D3
- Ubiquitin carrier protein D3
- ubiquitin-conjugating enzyme E2 D3
- Ubiquitin-conjugating enzyme E2(17)KB 3
- Ubiquitin-conjugating enzyme E2-17 kDa 3
- ubiquitin-conjugating enzyme E2D 3 (homologous to yeast UBC4/5)
- ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)
- Ubiquitin-protein ligase D3
Background
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Multiple spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined.