USP46 Antibody

Product: ARA290

USP46 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human USP46. The exact sequence is proprietary.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
USP46
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Immunohistochemistry 10 – 1:500
  • Immunohistochemistry-Paraffin 1:100-1:1000
Application Notes
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
42 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Expected cross reactivity based on sequence homology: Rhesus Monkey (100%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7.0), 0.1M Glycine and 20% Glycerol
Preservative
0.01% Thimerosal
Concentration
0.96 mg/ml
Purity
Immunogen affinity purified

Alternate Names for USP46 Antibody

  • Deubiquitinating enzyme 46
  • EC 3.1.2.15
  • EC 3.4.19.12
  • FLJ11850
  • FLJ12552
  • FLJ14283
  • FLJ39393
  • ubiquitin carboxyl-terminal hydrolase 46
  • ubiquitin specific peptidase 46
  • ubiquitin specific protease 46
  • ubiquitin thioesterase 46
  • Ubiquitin thiolesterase 46
  • Ubiquitin-specific-processing protease 46
  • USP46

Background

Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP46 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM]

PMID: 1982659