USP22 Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the center region of human USP22. The exact sequence is proprietary.
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| Predicted Species |
Mouse (98%), Rat (98%), Bovine (99%), Xenopus (97%). Backed by our 100% Guarantee.
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| Isotype |
IgG
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
USP22
|
| Purity |
Immunogen affinity purified
|
| Innovators Reward |
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|
Applications/Dilutions
| Dilutions |
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| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
|
| Theoretical MW |
60 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Reactivity Notes
Xenopus laevis (97%).
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.0), 1.0% BSA and 20% Glycerol
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| Preservative |
0.01% Thimerosal
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| Concentration |
1 mg/ml
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| Purity |
Immunogen affinity purified
|
Alternate Names for USP22 Antibody
- Deubiquitinating enzyme 22
- EC 3.1.2.15
- EC 3.4.19.12
- KIAA1063ubiquitin carboxyl-terminal hydrolase 22
- KIAA1064
- ubiquitin specific peptidase 22
- ubiquitin specific peptidase 3-like
- ubiquitin specific protease 22
- Ubiquitin Thioesterase 22
- Ubiquitin thiolesterase 22
- ubiquitin-specific processing protease 22
- Ubiquitin-specific-processing protease 22
- USP22
- USP3L
Background
Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression.