USP10 Antibody Summary
| Immunogen |
Antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human USP10. The immunogen is located within amino acids 30 – 80 of USP10.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
USP10
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Control Peptide |
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Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
PBS
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| Preservative |
0.02% Sodium Azide
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| Concentration |
1 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for USP10 Antibody
- Deubiquitinating enzyme 10
- EC 3.4.19.12
- KIAA0190MGC2621
- ubiquitin carboxyl-terminal hydrolase 10
- ubiquitin specific peptidase 10
- ubiquitin specific protease 10
- ubiquitin thioesterase 10
- Ubiquitin Thiolesterase 10
- Ubiquitin-specific-processing protease 10
- UBPO
- Uchrp
- USP10
Background
USP10, also known as ubiquitin specific peptidase 10, belongs to the ubiquitin-specific protease family of cysteine proteases. USP10 functions to catalyze the cleavage of ubiquitin from ubiquitin-conjugated protein substrates such as p53/TP53, SNX3 and CFTR. USP10 has been identified as a subunit of DNA-bound androgen receptor (AR) complexes and may play a role in the activity of the DNA-bound androgen receptor complex. USP10 also acts as an essential regulator of p53/TP53 stability and is thought to function as a tumor suppressor.