UCH-L1/PGP9.5 Antibody Summary
| Immunogen |
Recombinant full length human UCHL1 purified from E. coli.
|
| Marker |
pan-Neuronal Marker
|
| Specificity |
Specific for the ~24kDa UCHL1 protein.
|
| Clonality |
Polyclonal
|
| Host |
Chicken
|
| Gene |
UCHL1
|
| Purity |
IgG purified
|
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|
Applications/Dilutions
| Dilutions |
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Reactivity Notes
Tested in Bovine, Human and Rat. Expected reactivity to most mammals.
Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
|
| Buffer |
No buffer
|
| Preservative |
10mM Sodium Azide
|
| Purity |
IgG purified
|
Alternate Names for UCH-L1/PGP9.5 Antibody
- EC 3.4.19.12
- EC 6.-
- Neuron cytoplasmic protein 9.5
- PARK5
- PGP 9.5
- PGP9.5
- PGP9.5Uch-L1
- PGP95
- ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
- ubiquitin carboxyl-terminal hydrolase isozyme L1
- ubiquitin C-terminal hydrolase
- Ubiquitin thioesterase L1
- UCHL1
- UCH-L1
Background
PGP9.5 is a soluble cytoplasmic protein with a molecular weight of approximately 25,000 kD. It is present in neurons and in cells of the diffuse neuroendocrine system. PGP9.5 functions as a tissue-specific ubiquitin carboxyl terminal hydrolase isoenzyme. This enzyme is also known as UCH-L1. Because of its abundance in nerves, it has been widely used as a marker for peripheral nerve fibers