UBR1 Antibody (2F5) Summary
| Immunogen |
UBR1 (NP_777576, 2 a.a. ~ 101 a.a) partial recombinant protein with GST tag.ADEEAGGTERMEISAELPQTPQRLASWWDQQVDFYTAFLHHLAQLVPEIYFAEMDPDLEKQEESVQMSIFTPLEWYLFGEDPDICLEKLKHSGAFQLCG
|
| Specificity |
UBR1 – ubiquitin protein ligase E3 component n-recognin 1
|
| Isotype |
IgG1 Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
UBR1
|
| Purity |
IgG purified
|
| Innovators Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovators Reward
|
Applications/Dilutions
| Dilutions |
|
|
| Application Notes |
Antibody reactive against cell lysate and recombinant protein for western blot. It has also been used for ELISA.
|
|
| Publications |
|
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
IgG purified
|
Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for UBR1 Antibody (2F5)
- E3 ubiquitin-protein ligase UBR1
- E3a ligase
- EC 6.3.2.-
- JBS
- MGC142065
- MGC142067
- N-recognin-1
- ubiquitin ligase E3 alpha-I
- ubiquitin protein ligase E3 component n-recognin 1
- ubiquitin-protein ligase E3-alpha
- Ubiquitin-protein ligase E3-alpha-1
- Ubiquitin-protein ligase E3-alpha-I
Background
The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by this gene, binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. The protein described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome.