UBE2R2 Antibody (5E7) Summary
| Immunogen |
UBE2R2 (AAH47584, 1 a.a. ~ 239 a.a) full length recombinant protein with GST tag.MAQQQMTSSQKALMLELKSLQEEPVEGFRITLVDESDLYNWEVAIFGPPNTLYEGGYFKAHIKFPIDYPYSPPTFRFLTKMWHPNIYENGDVCISILHPPVDDPQSGELPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMFRKWRDSKGKDKEYAEIIRKQVSATKAEAEKDGVKVPTTLAEYCIKTKVPSNDNSSDLLYDDLYDDDIDDEDEEEEDADCYDDDDSGNEES
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| Specificity |
UBE2R2 – ubiquitin-conjugating enzyme E2R 2
|
| Isotype |
IgG2b Kappa
|
| Clonality |
Monoclonal
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| Host |
Mouse
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| Gene |
UBE2R2
|
| Purity |
IgG purified
|
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Applications/Dilutions
| Dilutions |
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| Application Notes |
Antibody reactive against cell lysate and recombinant protein for western blot. It has also been used for ELISA.
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Reactivity Notes
Human. Other species not tested.
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
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| Preservative |
No Preservative
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| Purity |
IgG purified
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Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for UBE2R2 Antibody (5E7)
- CDC34B
- CDC34BEC 6.3.2.19
- E2-CDC34B
- FLJ20419
- MGC10481
- UBC3B
- UBC3BUbiquitin-protein ligase R2
- UBE2R2
- Ubiquitin carrier protein R2
- ubiquitin-conjugating enzyme E2 R2
- Ubiquitin-conjugating enzyme E2-CDC34B
- ubiquitin-conjugating enzyme E2R 2
- ubiquitin-conjugating enzyme UBC3B
Background
Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation.