Troponin C (cardiac) Antibody (1F8-A9) Summary
| Immunogen |
TNNC1 (AAH30244, 1 a.a. – 161 a.a.) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MDDIYKAAVEQLTEEQKNEFKAAFDIFVLGAEDGCISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVDFDEFLVMMVRCMKDDSKGKSEEELSDLFRMFDKNADGYIDLDELKIMLQATGETITEDDIEELMKDGDKNNDGRIDYDEFLEFMKGVE
|
| Localization |
Cytoplasmic
|
| Specificity |
TNNC1 – troponin C, slow
|
| Isotype |
IgG1 Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
TNNC1
|
| Purity |
IgG purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Antibody reactivity against recombinant protein for WB. It has been used for IHC-P and ELISA.
|
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
IgG purified
|
Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for Troponin C (cardiac) Antibody (1F8-A9)
- cardiac troponin C
- CMD1Z
- CMH13
- slow twitch skeletal/cardiac muscle troponin C
- TNC
- TN-C
- TNNC
- troponin C type 1 (slow)
- troponin C, slow skeletal and cardiac muscles
- troponin C, slow
- troponin C1, slow
Background
Troponin I is part of a heteromeric complex playing an important role in the regulation of skeletal and cardiac muscle contraction. It consists of three subunits, troponin I (TnI), troponin T (TnT) and troponin C (TnC). Each subunit is responsible for part of troponin complex function. TnI inhibits ATPase activity of acto myosin and TnT and TnI are present in cardiac muscles in different forms than in skeletal muscles. Only one tissue specific isoform of TnI is described for cardiac muscle tissue (cTnI) and this is expressed only in myocardium.