TRAIL R1/TNFRSF10A Antibody Summary
| Immunogen |
This antibody is specific for the Middle Region of the target protein.
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| Specificity |
This product is specific for Human TNFRSF10A.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
TNFRSF10A
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
This antibody is useful in ELISA, Western Blot and Immunohistochemistry-Paraffin.
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| Publications |
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Reactivity Notes
Human.
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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| Buffer |
20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
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| Preservative |
No Preservative
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| Purity |
Immunogen affinity purified
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Notes
Manufactured by SDIXs proprietary Genomic Antibody Technology™. GAT FAQs.
Alternate Names for TRAIL R1/TNFRSF10A Antibody
- APO2
- CD261 antigen
- CD261
- cytotoxic TRAIL receptor
- Death receptor 4
- DR4 TRAIL receptor 1
- DR4
- TNF-related apoptosis inducing ligand receptor 1
- TNF-related apoptosis-inducing ligand receptor 1
- TNFRSF10A
- TRAIL R1
- TRAILR1
- TRAIL-R1
- TRAILR-1
- TRAILR1MGC9365
- tumor necrosis factor receptor superfamily member 10A
- tumor necrosis factor receptor superfamily, member 10a
Background
Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel cell death receptor was recently identified and designated DR4 (for death receptor 4). The ligand for this novel death receptor has been identified and termed TRAIL-R1, which is a new member in the TNF family. DR4 is also called TRAIL receptor 1(TRAIL R1). DR4 is expressed in most of human tissues including spleen, peripheral blood leukocytes, small intestine and thymus. Like TNFR1, Fas and DR3, DR4 mediates apoptosis and NF kB activation in many tissues and cells.