TRAF-4 Antibody Summary
| Immunogen |
TRAF4 (NP_004286.2, 1 a.a. ~ 470 a.a) full-length human protein.MPGFDYKFLEKPKRRLLCPLCGKPMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPEDQLPLDYAKIYPDPELEVQVLGLPIRCIHSEEGCRWSGPLRHLQGHLNTCSFNVIPCPNRCPMKLSRRDLPAHLQHDCPKRRLKCEFCGCDFSGEAYESHEGMCPQESVYCENKCGARMMRRLLAQHATSECPKRTQPCTYCTKEFVFDTIQSHQYQCPRLPVACPNQCGVGTVAREDLPGHLKDSCNTALVLCPFKDS
|
| Specificity |
TRAF4 – TNF receptor-associated factor 4,
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
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| Gene |
TRAF4
|
| Purity |
Protein A purified
|
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Applications/Dilutions
| Dilutions |
|
| Application Notes |
Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control.
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Reactivity Notes
Human.
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
Protein A purified
|
Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for TRAF-4 Antibody
- CART1
- CART1RING finger protein 83
- Cysteine-rich domain associated with RING and Traf domains protein 1
- Metastatic lymph node gene 62 protein
- MLN 62
- MLN62
- MLN62cysteine-rich domain associated with ring and TRAF domain
- RNF83malignant 62
- TNF receptor-associated factor 4
- TRAF4
- TRAF-4
- tumor necrosis receptor-associated factor 4A
Background
This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined. [provided by RefSeq]