TLR9 Antibody (1E8) Summary
| Immunogen |
TLR9 (AAH32713, 99 a.a. ~ 215 a.a) partial recombinant protein with GST tag.PPVGLSPMHFPCHMTIEPSTFLAVPTLEELNLSYNNIMTVPALPKSLISLSLSHTNILMLDSASLAGLHALRFLFMDGNCYYKNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVP
|
| Specificity |
TLR9 (1E8)
|
| Isotype |
IgG2a Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
TLR9
|
| Purity |
IgG purified
|
| Innovators Reward |
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Applications/Dilutions
| Dilutions |
|
| Application Notes |
Antibody reactive against cell lysate for Western Blot. Has also been used for immunofluoresence and ELISA.
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| Agonist |
|
Reactivity Notes
Human. Other species not tested.
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
IgG purified
|
Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for TLR9 Antibody (1E8)
- CD289 antigen
- CD289
- TLR9
- toll-like receptor 9
Background
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.