TLR11 Antibody

Product: EGF817

TLR11 Antibody Summary

Immunogen
Antibody was raised against a peptide corresponding to 16 amino acids between the middle and carboxy terminus of mouse TLR11. The immunogen is located within the last 50 amino acids of TLR11.
Clonality
Polyclonal
Host
Rabbit
Gene
TLR11
Purity
Ion exchange chromatography
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 1:10-1:2000
  • Immunofluorescence 10 ug/ml
Application Notes
TLR11 antibody polyclonal antibody can be used for detection of TLR11 by Western blot at 0.5 to 2 mg/ml.
Control Peptide
TLR11 Peptide (NBP1-77202PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Ion exchange chromatography

Alternate Names for TLR11 Antibody

  • Gm287
  • hgnc31753
  • TLR11
  • Toll like receptor 11

Background

Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR11 is one of three mouse TLRs that lack a human ortholog. It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptability to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system.

PMID: 17975007