TFII-I Antibody Summary
| Immunogen |
A synthetic peptide, which represented a portion of human general transcription factor II-I encoded within exons 32 and 33 (LocusLink ID 2969).
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| Predicted Species |
Rat (100%), Bat (100%), Primate (100%). Backed by our 100% Guarantee.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
GTF2I
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
By Western Blot, this antibody recognizes a band at ~135 kDa, representing TFII-I. *The investigator should determine the optimal working dilution for a specific application.
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| Positive Control |
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Reactivity Notes
Based on 100% sequence identity, this antibody is predicted to react with Rat, Orangutan, Rhesus Monkey, Chimpanzee, White-tufted-ear marmoset, Crab-eating macaque, Small-eared galago, Little brown bat and Northern white-cheeked gibbon.
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
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| Buffer |
Tris-Citrate/Phosphate (pH 7.0 – 8.0)
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| Preservative |
0.09% Sodium Azide
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| Concentration |
1.0 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for TFII-I Antibody
- BAP-135,135kD
- BAP135WBS
- Bruton tyrosine kinase-associated protein 135
- BTKAP1
- DIWS
- FLJ38776
- FLJ56355
- general transcription factor II, i
- general transcription factor IIi
- general transcription factor II-I
- GTFII-I
- IB291
- SPINBTK-associated protein 135
- TFII-ISRF-Phox1-interacting protein
- WBSCR6
- Williams-Beuren syndrome chromosome region 6
Background
TFII-I is an unusual transcription factor possessing both basal and signal-induced transcriptional functions. It is a founding member of a family of transcription factors characterized by the presence of multiple helix-loop-helix repeat domains. It is involved in histone modification and SUMOylation. TFII-I expression also plays a role in preimplantation development and has been detected in the cytoplasm and nuclei of post-fertilization through first cleavage stage embryos.