Product: Cabozantinib (S-malate)
Skp1 Antibody (1H8) Summary
| Immunogen |
SKP1A (NP_008861, 53 a.a. – 160 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. AILKKVIQWCTHHKDDPPPPEDDENKEKRTDDIPVWDQEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMIKGKTPEEIRKTFNIKNDFTEEEEAQVGSTQFCL
|
| Specificity |
SKP1A – S-phase kinase-associated protein 1A (p19A)
|
| Isotype |
IgG2a Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
SKP1
|
| Purity |
IgG purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for IF and ELISA.
|
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
IgG purified
|
Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for Skp1 Antibody (1H8)
- Cyclin-A/CDK2-associated protein p19
- EMC19p19skp1
- MGC34403
- OCP2OCP-2
- OCP-IIS-phase kinase-associated protein 1A (p19A)
- Organ of Corti protein 2
- Organ of Corti protein II
- p19Acyclin A/CDK2-associated p19
- RNA polymerase II elongation factor-like protein OCP2
- RNA polymerase II elongation factor-like protein
- SKP1Acyclin A/CDK2-associated protein p19
- S-phase kinase-associated protein 1
- TCEB1LSIII
- Transcription elongation factor B
Background
This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7.