Sigma-1 R/OPRS1 Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the center region of human SIGMAR1. The exact sequence is proprietary.
|
| Localization |
Nucleus inner membrane; Nucleus outer membrane; Endoplasmic reticulum membrane; Lipid droplet; Cell junction; Cell membrane; Cell projection; growth cone
|
| Predicted Species |
Mouse (94%), Rat (96%), Bovine (97%), Monkey (100%), Guinea Pig (96%). Backed by our 100% Guarantee.
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
SIGMAR1
|
| Purity |
Immunogen affinity purified
|
| Innovators Reward |
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
|
| Theoretical MW |
25 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Reactivity Notes
Rhesus Monkey (100%).
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
0.1M Tris (pH 7.0), 0.1M Glycine and 20% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
1 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for Sigma-1 R/OPRS1 Antibody
- Aging-associated gene 8 protein
- ALS16
- FLJ25585
- hSigmaR1
- OPRS1
- SIG-1R
- sigma 1
- Sigma 1-type opioid receptor
- sigma non-opioid intracellular receptor 1
- Sigma-1 R
- sigma1 receptor
- Sigma1R
- Sigma-1R
- sigma1-receptor
- SIGMAR1
- SR31747 binding protein 1
- SR31747-binding protein
- SRBP
- SR-BP
- SR-BP1
- SRBPMGC3851
- type I sigma receptor
Background
This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Alternative splicing of this gene results in transcript variants encoding distinct isoforms. [provided by RefSeq]