STAM2 Antibody

Product: SB-408124

STAM2 Antibody Summary

Immunogen
Peptide with sequence C-QSIDPTDSKPDSQD corresponding to internal region according to NP_005834.3.
Specificity
No cross-reaction expected with STAM1.
Clonality
Polyclonal
Host
Goat
Gene
STAM2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1 – 3 ug/ml
  • Peptide ELISA Detection limit 1:8000
Application Notes
WB: Approx. 70 kDa band observed in human spleen lysates is reported in scientific literature (PMID: 10993906).
Positive Control
STAM2 Lysate (NBL1-16510)
Spleen Lysate (NB820-59259)
Publications
Read Publications using NB100-2838.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Mouse, Canine.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for STAM2 Antibody

  • DKFZp564C047
  • Hbp
  • Hrs-binding protein
  • HSE1 homolog
  • signal transducing adapter molecule 2
  • signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
  • STAM-2
  • STAM2A
  • STAM2B
  • STAM-like protein containing SH3 and ITAM domains 2

Background

The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation.

PMID: 21216834