SMG1 Antibody (1C12)

Product: Lapatinib

SMG1 Antibody (1C12) Summary

Immunogen
SMG1 (-, 2922 a.a. ~ 3032 a.a) partial recombinant protein with GST tag.PDVMSQNARKLIQKNLATSADTPPSTVPGTGKSVACSPKKAVRDPKTGKAVQERNSYAVSVWKRVKAKLEGRDVDPNRRMSVAEQVDYVIKEATNLDNLAQLYEGWTAWV
Specificity
SMG1 (1C12)
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
SMG1
Purity
IgG purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:500
  • ELISA
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Antibody reactive against cell lysate and recombinant protein for western blot. It has also been used for ELISA and immunohistochemistry (paraffin).

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for SMG1 Antibody (1C12)

  • ATXserine/threonine-protein kinase SMG1
  • EC 2.7.11
  • EC 2.7.11.1
  • hSMG-1,61E3.4
  • KIAA0421phosphatidylinositol 3-kinase-related protein kinase
  • Lambda/iota protein kinase C-interacting protein
  • Lambda-interacting protein
  • LIPPI-3-kinase-related kinase SMG-1
  • phosphatidylinositol 3-kinase-related kinase
  • SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)
  • SMG-1

Background

This gene encodes a protein involved in nonsense-mediated mRNA decay (NMD) as part of the mRNA surveillance complex. The protein has kinase activity and is thought to function in NMD by phosphorylating the regulator of nonsense transcripts 1 protein. Alternative spliced transcript variants have been described, but their full-length natures have not been determined.

PMID: 22366722